10.1021/ol302011b.s001
Graham K. Murphy
Graham K.
Murphy
Naoto Hama
Naoto
Hama
Aaron Bedermann
Aaron
Bedermann
Ping Dong
Ping
Dong
Chris M. Schneider
Chris M.
Schneider
Travis C. McMahon
Travis C.
McMahon
Ran N. Tao
Ran N.
Tao
Barry M. Twenter
Barry M.
Twenter
David A. Spiegel
David A.
Spiegel
John L. Wood
John L.
Wood
Wharton-Fragmentation-Based Approach to the Carbocyclic Core of the Phomoidrides
American Chemical Society
2012
sequence
phomoidride
Approach
Key steps
cyclization
Wharton
Diel
Carbocyclic Core
phenolic
oxidation
tandem
fragmentation
PhomoidridesThe carbocyclic core
functionalized isotwistane skeleton
2012-09-07 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Wharton_Fragmentation_Based_Approach_to_the_Carbocyclic_Core_of_the_Phomoidrides/2489701
The carbocyclic core of the phomoidrides has been synthesized efficiently and in high yield. Key steps include a phenolic oxidation/intramolecular Diels–Alder sequence, tandem radical cyclization, and a late-stage Wharton fragmentation of a densely functionalized isotwistane skeleton.