Synthesis of Substituted
Phenanthrene by Iron(III)-Catalyzed
Intramolecular Alkyne–Carbonyl Metathesis
Krishnendu Bera
Soumen Sarkar
Swapnadeep Jalal
Umasish Jana
10.1021/jo301371n.s001
https://acs.figshare.com/articles/dataset/Synthesis_of_Substituted_Phenanthrene_by_Iron_III_Catalyzed_Intramolecular_Alkyne_Carbonyl_Metathesis/2480548
An efficient synthesis of functionalized phenanthrenes
has been
developed for the first time involving an iron(III)-catalyzed intramolecular
coupling of 2′-alkynyl-biphenyl-2-carbaldehydes. A broad range
of functionalized phenanthrene derivatives could be obtained in the
present method in moderate to good yields with high chemo- and regioselectivity.
This transformation can also be applied to the synthesis of an angularly
fused tetracyclic compound. This method offers several advantages
such as high selectivity, mild reaction conditions, and easy availability
of starting materials.
2012-10-05 00:00:00
reaction conditions
selectivity
intramolecular
angularly
tetracyclic compound
availability
regioselectivity
material
Substituted Phenanthrene
functionalized phenanthrene derivatives
MetathesisAn
method
synthesis
chemo
Alkyne
functionalized phenanthrenes
yield
transformation
Intramolecular
Synthesi