%0 Journal Article
%A Ren, Jinwei
%A Zhang, Fan
%A Liu, Xiangyu
%A Li, Li
%A Liu, Gang
%A Liu, Xingzhong
%A Che, Yongsheng
%D 2012
%T Neonectrolide A, a New Oxaphenalenone Spiroketal from the Fungus Neonectria sp.
%U https://acs.figshare.com/articles/journal_contribution/Neonectrolide_A_a_New_Oxaphenalenone_Spiroketal_from_the_Fungus_i_Neonectria_i_sp_/2458588
%R 10.1021/ol302979f.s001
%2 https://ndownloader.figshare.com/files/4101268
%K skeleton
%K dimethyl
%K fungus Neonectria sp
%K culture
%K New Oxaphenalenone Spiroketal
%K acid
%K moiety
%K ECD
%K coisolated
%K dichroism
%K calculation
%K corymbiferan
%K Fungus Neonectria sp.Neonectrolide
%K lactone
%K oxaphenalenone spiroketal
%K configuration
%K undescribed
%K dehydroxy
%K dioxaspiro
%K precursor
%X Neonectrolide A (1), an oxaphenalenone spiroketal with the previously undescribed (5,8′-dimethyl-5′-oxo-3a′,4,5,5′-tetrahydro-3H,3′H-spiro[furan-2,2′-isochromeno[3,4,5-def]chromene]-3′-yl)but-3-enoic acid skeleton, was isolated from cultures of the fungus Neonectria sp. Its absolute configuration was assigned by electronic circular dichroism (ECD) calculations. The skeleton of an oxaphenalenone fused with a 1,6-dioxaspiro[4.5]decane moiety in 1 could be derived from the coisolated putative precursors, corymbiferan lactone E (2) and 3-dehydroxy-4-O-acetylcephalosporolide C (3).
%I ACS Publications