10.1021/ja401385v.s001 Maciej A. Walczak Maciej A. Walczak Joji Hayashida Joji Hayashida Samuel J. Danishefsky Samuel J. Danishefsky Building Biologics by Chemical Synthesis: Practical Preparation of Di- and Triantennary <i>N</i>‑Linked Glycoconjugates American Chemical Society 2013 glycosylation strategy triantennary PSMA oligopeptide conjugation Chemical Synthesis Di sialylated Practical Preparation synthesis glycan synthese undeca GlycoconjugatesA Triantennary tetradecasaccharide building Biologics yield 2013-03-27 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Building_Biologics_by_Chemical_Synthesis_Practical_Preparation_of_Di_and_Triantennary_i_N_i_Linked_Glycoconjugates/2430811 A unified strategy for the syntheses of bi- and triantennary fully sialylated <i>N</i>-glycans is described. The synthesis capitalizes on a global glycosylation strategy that delivers the desired undeca- and tetradecasaccharide in excellent yields. Finally, conjugation of the glycan to PSMA oligopeptide is described.