10.1021/ja406761j.s001
Yongbing Liu
Yongbing
Liu
Haifeng Du
Haifeng
Du
Metal-Free Borane-Catalyzed Highly Stereoselective
Hydrogenation of Pyridines
American Chemical Society
2013
Stereoselective Hydrogenation
HB
cis stereoselectivities
piperidine
hydrogenation
alkene
hydroboration
pyridine
PyridinesA
yield
borane catalysts
2013-09-04 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Metal_Free_Borane_Catalyzed_Highly_Stereoselective_Hydrogenation_of_Pyridines/2381425
A metal-free
direct hydrogenation of pyridines was successfully
realized by using homogeneous borane catalysts generated from alkenes
and HBÂ(C<sub>6</sub>F<sub>5</sub>)<sub>2</sub> via in situ hydroboration.
The reaction affords a broad range of piperidines in high yields with
excellent cis stereoselectivities.