Highly Sensitive Detection of Physiological Spins
in a Microfluidic Device
Florestan C. Ziem
Nicolas S. Götz
Andrea Zappe
Steffen Steinert
Jörg Wrachtrup
10.1021/nl401522a.s001
https://acs.figshare.com/articles/journal_contribution/Highly_Sensitive_Detection_of_Physiological_Spins_in_a_Microfluidic_Device/2378134
Sensing and imaging paramagnetic
species under physiological conditions
is a key technology in chemical and biochemical analytics, cell biology,
and medical sciences. At submicrometer length scales, nitrogen-vacancy
(NV) centers in diamond offer atom-sized probes for magnetic fields.
We show that spin relaxation of an ensemble NV sensor allows sensing
of adsorbed and freely diffusing manganese(II) ions and adsorbed ferritin.
Sensitivities approach 175 Mn ions and 10 ferritin proteins per diffraction
limited spot under ambient conditions.
2013-09-11 00:00:00
probe
Sensitive Detection
technology
species
Physiological Spins
cell biology
Sensitivities approach 175 Mn ions
analytic
ambient conditions
imaging
ensemble NV sensor
relaxation
submicrometer length scales
center
Microfluidic DeviceSensing
diffraction
manganese
chemical
10 ferritin proteins