%0 Journal Article %A Pan, Changduo %A Han, Jie %A Zhang, Honglin %A Zhu, Chengjian %D 2014 %T Radical Arylalkoxycarbonylation of 2‑Isocyanobiphenyl with Carbazates: Dual C–C Bond Formation toward Phenanthridine-6-carboxylates %U https://acs.figshare.com/articles/journal_contribution/Radical_Arylalkoxycarbonylation_of_2_Isocyanobiphenyl_with_Carbazates_Dual_C_C_Bond_Formation_toward_Phenanthridine_6_carboxylates/2285440 %R 10.1021/jo500842e.s001 %2 https://ndownloader.figshare.com/files/3921943 %K reaction conditions %K trifluoromethyl groups %K Radical Arylalkoxycarbonylation %K strategy %K access %K sequential %K isocyanobiphenyl %K carbazate %K Phenanthridine %K methoxy %K trifluoromethoxy %K chloro %K Carbazate %K oxidative %K Bond %K phenanthridine %K Formation %K Dual %K Isocyanobiphenyl %K aromatization %X A sequential oxidative radical alkoxycarbonylation and aromatization of 2-isocyanobiphenyl with carbazates was developed to furnish phenanthridine-6-carboxylates. Various functional groups such as methoxy, chloro, fluoro, trifluoromethoxy, and trifluoromethyl groups were tolerated well under the reaction conditions. The sequential radical addition–cyclization strategy represents a practical route to access phenanthridine-6-carboxylates. %I ACS Publications