TY - DATA T1 - Expedient Synthesis of Pyrroloquinolinones by Rh-Catalyzed Annulation of N‑Carbamoyl Indolines with Alkynes through a Directed C–H Functionalization/C–N Cleavage Sequence PY - 2015/03/20 AU - Xiao-Fei Yang AU - Xu-Hong Hu AU - Teck-Peng Loh UR - https://acs.figshare.com/articles/dataset/Expedient_Synthesis_of_Pyrroloquinolinones_by_Rh_Catalyzed_Annulation_of_i_N_i_Carbamoyl_Indolines_with_Alkynes_through_a_Directed_C_H_Functionalization_C_N_Cleavage_Sequence/2184442 DO - 10.1021/acs.orglett.5b00355.s004 L4 - https://ndownloader.figshare.com/files/3818608 KW - Indoline KW - Annulation KW - selectivity KW - Expedient Synthesis KW - Functionalization KW - analogue KW - indoline KW - sequential cleavage KW - Pyrroloquinolinone KW - strategy KW - functionalization KW - SequenceA KW - Alkyne KW - efficiency KW - pyrrolo KW - Cleavage KW - alkyne KW - urea motif KW - alkenylation KW - bond N2 - A Rh-catalyzed redox-neutral C–H functionalization of N-carbamoyl indolines with various internal alkynes has been developed. The reaction, which involves the sequential cleavage of the C–H bond of the indoline at the C7-position and the C–N bond of the urea motif, provides a divergent protocol to rapidly assemble fused-ring pyrrolo­quinolinone analogues by using a direct alkenylation/annulation strategy with high efficiency and selectivity. ER -