%0 Journal Article
%A Liu, Rui
%A Lu, Ze-Hai
%A Hu, Xiao-Hui
%A Li, Jun-Li
%A Yang, Xian-Jin
%D 2015
%T Monocarboxylation and Intramolecular Coupling of Butenylated
Arenes via Palladium-Catalyzed C–H Activation Process
%U https://acs.figshare.com/articles/journal_contribution/Monocarboxylation_and_Intramolecular_Coupling_of_Butenylated_Arenes_via_Palladium_Catalyzed_C_H_Activation_Process/2184436
%R 10.1021/acs.orglett.5b00376.s001
%2 https://ndownloader.figshare.com/files/3818602
%K esters
%K carboxylic
%K Butenylated
%K intramolecular
%K Pd
%K ProcessA
%K acid
%K research
%K tetralyl
%K Activation
%K butenylated arenes
%K method
%K synthesis
%K Arene
%K CH 3CN solution
%K catalysi
%K reagent
%K compound
%K oxidative
%K Monocarboxylation
%K bioactive
%K yield
%K Intramolecular
%K Selectfluor
%K monocarboxylation
%X A novel
and practical reaction for the direct intramolecular oxidative coupling
of butenylated arenes is reported. With the catalysis of Pd(OAc)2, reactions of various butenylated arenes and carboxylic acids
with Selectfluor reagent in CH3CN solution afforded the
corresponding monocarboxylation/cyclization products in good yields
under mild conditions. This research demonstrated an economic method
with the synthesis of 2-tetralyl carboxylic esters, a valuable class
of bioactive compounds.
%I ACS Publications