%0 Journal Article %A Liu, Rui %A Lu, Ze-Hai %A Hu, Xiao-Hui %A Li, Jun-Li %A Yang, Xian-Jin %D 2015 %T Monocarboxylation and Intramolecular Coupling of Butenylated Arenes via Palladium-Catalyzed C–H Activation Process %U https://acs.figshare.com/articles/journal_contribution/Monocarboxylation_and_Intramolecular_Coupling_of_Butenylated_Arenes_via_Palladium_Catalyzed_C_H_Activation_Process/2184436 %R 10.1021/acs.orglett.5b00376.s001 %2 https://ndownloader.figshare.com/files/3818602 %K esters %K carboxylic %K Butenylated %K intramolecular %K Pd %K ProcessA %K acid %K research %K tetralyl %K Activation %K butenylated arenes %K method %K synthesis %K Arene %K CH 3CN solution %K catalysi %K reagent %K compound %K oxidative %K Monocarboxylation %K bioactive %K yield %K Intramolecular %K Selectfluor %K monocarboxylation %X A novel and practical reaction for the direct intramolecular oxidative coupling of butenylated arenes is reported. With the catalysis of Pd­(OAc)2, reactions of various butenylated arenes and carboxylic acids with Selectfluor reagent in CH3CN solution afforded the corresponding monocarboxylation/cyclization products in good yields under mild conditions. This research demonstrated an economic method with the synthesis of 2-tetralyl carboxylic esters, a valuable class of bioactive compounds. %I ACS Publications