TY - DATA T1 - Influence of Molecular Structure on the Properties of Out-of-Equilibrium Oscillating Enzymatic Reaction Networks PY - 2015/09/30 AU - Albert S. Y. Wong AU - Sjoerd G. J. Postma AU - Ilia N. Vialshin AU - Sergey N. Semenov AU - Wilhelm T. S. Huck UR - https://acs.figshare.com/articles/journal_contribution/Influence_of_Molecular_Structure_on_the_Properties_of_Out_of_Equilibrium_Oscillating_Enzymatic_Reaction_Networks/2127388 DO - 10.1021/jacs.5b08129.s001 L4 - https://ndownloader.figshare.com/files/3761191 KW - case oscillations KW - reaction rates KW - reaction networks KW - network output KW - Molecular Structure KW - nonlinear systems KW - network behavior KW - Reaction NetworksOur knowledge KW - chemical reactions networks KW - chemical reactions N2 - Our knowledge of the properties and dynamics of complex molecular reaction networks, for example those found in living systems, considerably lags behind the understanding of elementary chemical reactions. In part, this is because chemical reactions networks are nonlinear systems that operate under conditions far from equilibrium. Of particular interest is the role of individual reaction rates on the stability of the network output. In this research we use a rational approach combined with computational methods, to produce complex behavior (in our case oscillations) and show that small changes in molecular structure are sufficient to impart large changes in network behavior. ER -