Photoresponsive
Molecular Switch for Regulating Transmembrane
Proton-Transfer Kinetics
Ying Li
Edmund C. M. Tse
Christopher
J. Barile
Andrew A. Gewirth
Steven C. Zimmerman
10.1021/jacs.5b10016.s001
https://acs.figshare.com/articles/journal_contribution/Photoresponsive_Molecular_Switch_for_Regulating_Transmembrane_Proton_Transfer_Kinetics/2110015
To
control proton delivery across biological membranes, we synthesized
a photoresponsive molecular switch and incorporated it in a lipid
layer. This proton gate was reversibly activated with 390 nm light
(<i>Z</i>-isomer) and then deactivated by 360 nm irradiation
(<i>E</i>-isomer). In a lipid layer this stimuli responsive
proton gate allowed the regulation of proton flux with irradiation
to a lipid-buried O<sub>2</sub> reduction electrocatalyst. Thus, the
catalyst was turned on and off with the <i>E</i>-to-<i>Z</i> interconversion. This light-induced membrane proton delivery
system may be useful in developing any functional device that performs
proton-coupled electron-transfer reactions.
2015-11-11 00:00:00
390 nm light
membrane
Photoresponsive Molecular Switch
360 nm irradiation
proton gate
lipid layer