%0 Journal Article
%A Xia, Xiao-Feng
%A Zhu, Su-Li
%A Chen, Chao
%A Wang, Haijun
%A Liang, Yong-Min
%D 2016
%T Silver-Catalyzed Decarboxylative
Addition/Cyclization of Activated Alkenes with Aliphatic
Carboxylic Acids
%U https://acs.figshare.com/articles/journal_contribution/Silver_Catalyzed_Decarboxylative_Addition_Cyclization_of_Activated_Alkenes_with_Aliphatic_Carboxylic_Acids/2071225
%R 10.1021/acs.joc.5b02594.s001
%2 https://ndownloader.figshare.com/files/3700057
%K stereocenter
%K migration
%K Decarboxylative
%K carboxylic acids
%K AcidsA
%K decarboxylation
%K decarboxylative
%K approach
%K synthesis
%K Activated Alkenes
%K isoquinolinedione
%K amide
%K Carboxylic
%K Aliphatic
%K quaternary
%K sequence reaction
%X A silver-catalyzed
decarboxylative addition/aryl migration/desulfonylation
of N-phenyl-N-(phenylsulfonyl)methacrylamide
with primary, secondary, and tertiary carboxylic acids was described.
The protocol provides an efficient approach for the synthesis of α-all-carbon
quaternary stereocenters amides and isoquinolinediones. It was proposed
that the radical generated from the silver-catalyzed decarboxylation
was involved in the sequence reaction.
%I ACS Publications