%0 Journal Article %A Xia, Xiao-Feng %A Zhu, Su-Li %A Chen, Chao %A Wang, Haijun %A Liang, Yong-Min %D 2016 %T Silver-Catalyzed Decarboxylative Addition/Cyclization of Activated Alkenes with Aliphatic Carboxylic Acids %U https://acs.figshare.com/articles/journal_contribution/Silver_Catalyzed_Decarboxylative_Addition_Cyclization_of_Activated_Alkenes_with_Aliphatic_Carboxylic_Acids/2071225 %R 10.1021/acs.joc.5b02594.s001 %2 https://ndownloader.figshare.com/files/3700057 %K stereocenter %K migration %K Decarboxylative %K carboxylic acids %K AcidsA %K decarboxylation %K decarboxylative %K approach %K synthesis %K Activated Alkenes %K isoquinolinedione %K amide %K Carboxylic %K Aliphatic %K quaternary %K sequence reaction %X A silver-catalyzed decarboxylative addition/aryl migration/desulfonylation of N-phenyl-N-(phenyl­sulfonyl)­methacrylamide with primary, secondary, and tertiary carboxylic acids was described. The protocol provides an efficient approach for the synthesis of α-all-carbon quaternary stereocenters amides and isoquinolinediones. It was proposed that the radical generated from the silver-catalyzed decarboxylation was involved in the sequence reaction. %I ACS Publications