Brown, Casey J. Kokai, Akos Miller, Gregory M. Bergman, Robert G. Raymond, Kenneth N. Improved scope and diastereoselectivity of C–H activation in an expanded supramolecular host <p>Chiral Ga<sub>4</sub>L<sub>6</sub> assembly Ga<sub>4</sub>(L<sup>N</sup>)<sub>6</sub> encapsulates cationic iridium half-sandwich complexes that activate aldehyde C–H bonds to form chiral, strongly bound piano-stool complexes. Herein, we report the expanded scope of the larger Ga<sub>4</sub>(L<sup>P</sup>)<sub>6</sub> host in mediating this transformation. The larger assembly significantly improves both the scope and the diastereoselectivity of this organometallic transformation generally, while substrate-specific interactions demonstrate that host size is an important, but not definitive, factor in determining diastereoselectivity.</p> supramolecular catalysis;organometallic chemistry;C–H activation 2016-01-29
    https://tandf.figshare.com/articles/journal_contribution/Improved_scope_and_diastereoselectivity_of_C_H_activation_in_an_expanded_supramolecular_host/2068773
10.6084/m9.figshare.2068773.v1