10.1371/journal.pone.0045512.g004
Sheng-Lin Lee
Sheng-Lin
Lee
Ali Nekouzadeh
Ali
Nekouzadeh
Boyd Butler
Boyd
Butler
Kenneth M. Pryse
Kenneth
M. Pryse
William B. McConnaughey
William
B. McConnaughey
Adam C. Nathan
Adam
C. Nathan
Wesley R. Legant
Wesley R.
Legant
Pascal M. Schaefer
Pascal
M. Schaefer
Robert B. Pless
Robert
B. Pless
Elliot L. Elson
Elliot
L. Elson
Guy M. Genin
Guy
M. Genin
The three classes of dynamic cellular response could be captured by the model for all cell shapes considered, including circular (top row) and spindle-shaped (bottom row) cells.
Public Library of Science
2012
classes
cellular
captured
shapes
circular
spindle-shaped
2012-12-27 02:01:07
Figure
https://plos.figshare.com/articles/figure/_The_three_classes_of_dynamic_cellular_response_could_be_captured_by_the_model_for_all_cell_shapes_considered_including_circular_top_row_and_spindle_shaped_bottom_row_cells_/187267
<p>Populations of stress fibers were studied with the same mean pre-stretch, but with three different standard deviations. Monotonic reinforcement (first column), reinforcement followed by retraction (second column), and monotonic retraction (third column) were all predicted, depending upon the variation in pre-stretch within the fibers. Cells in which many stress fibers ruptured in tension underwent monotonic retraction. Cells in which no stress fibers ruptured in tension underwent monotonic reinforcement. All other cellular responses lay between these two extremes, and involved reinforcement following retraction.</p>