10.1371/journal.pone.0054506.g003 Erkko Ylösmäki Erkko Ylösmäki Sergio Lavilla-Alonso Sergio Lavilla-Alonso Sari Jäämaa Sari Jäämaa Markus Vähä-Koskela Markus Vähä-Koskela Taija af Hällström Taija af Hällström Akseli Hemminki Akseli Hemminki Johanna Arola Johanna Arola Heikki Mäkisalo Heikki Mäkisalo Kalle Saksela Kalle Saksela Immunohistochemical analysis of Ad5 and Ad5T122 infection in ex vivo tissue cultures of normal human liver and colorectal carcinoma liver metastasis. Public Library of Science 2013 ad5 ad5t122 ex vivo cultures colorectal carcinoma 2013-01-22 01:07:46 Figure https://plos.figshare.com/articles/figure/_Immunohistochemical_analysis_of_Ad5_and_Ad5T122_infection_in_ex_vivo_tissue_cultures_of_normal_human_liver_and_colorectal_carcinoma_liver_metastasis_/174066 <p>Precision-cut tumour (top and third row of panels) and liver (second row and bottom panels) tissue cultures were left uninfected (left panels) or infected with 10<sup>7</sup> PFU (in 2 ml of media) of Ad5 (middle panels) or Ad5T122 (right panels), and fixed five days later for staining with haematoxylin-eosin (panels G-L) or an antibody against the viral E1A protein (panels A–F). Necrosis developing in the central area of the uninfected control tissue (panel J) is indicated with arrows.</p>