%0 Figure %A Bilsland, Elizabeth %A M. Bean, Daniel %A Devaney, Eileen %A G. Oliver, Stephen %D 2016 %T Validation of the hit compounds using Brugia pahangi adult female worms. %U https://plos.figshare.com/articles/figure/_Validation_of_the_hit_compounds_using_Brugia_pahangi_adult_female_worms_/1642736 %R 10.1371/journal.pntd.0004401.g005 %2 https://ndownloader.figshare.com/files/2634836 %K World Health Organization %K filarial %K compound %K aid antihelmintic drug development %K Brugia malayi drug targets %K contracting lymphatic filariasis %K complement yeast deletions %K Identify Novel Compounds %K Brugia malayi BackgroundLymphatic filariasis %K strain %K parasite enzymes %K worms Wuchereria bancrofti %K Brugia malayi enzymes %X

Chemical structures were obtained from www.chemspider.com. The IC50 for each of the compounds in human fibroblasts (MRC5) is shown in the last column [26]. The IC50 of Geldanamycin against different human cell lines is a consensus of multiple data available in the literature (www.medchemexpress.com/Geldanamycin.html).

%I PLOS Neglected Tropical Diseases