10.1371/journal.ppat.1005369.g002
Elise Landais
Elise
Landais
Xiayu Huang
Xiayu
Huang
Colin Havenar-Daughton
Colin
Havenar-Daughton
Ben Murrell
Ben
Murrell
Matt A. Price
Matt
A. Price
Lalinda Wickramasinghe
Lalinda
Wickramasinghe
Alejandra Ramos
Alejandra
Ramos
Charoan B. Bian
Charoan
B. Bian
Melissa Simek
Melissa
Simek
Susan Allen
Susan
Allen
Etienne Karita
Etienne
Karita
William Kilembe
William
Kilembe
Shabir Lakhi
Shabir
Lakhi
Mubiana Inambao
Mubiana
Inambao
Anatoli Kamali
Anatoli
Kamali
Eduard J. Sanders
Eduard
J. Sanders
Omu Anzala
Omu
Anzala
Vinodh Edward
Vinodh
Edward
Linda-Gail Bekker
Linda-Gail
Bekker
Jianming Tang
Jianming
Tang
Jill Gilmour
Jill
Gilmour
Sergei L. Kosakovsky-Pond
Sergei
L. Kosakovsky-Pond
Pham Phung
Pham
Phung
Terri Wrin
Terri
Wrin
Shane Crotty
Shane
Crotty
Adam Godzik
Adam
Godzik
Pascal Poignard
Pascal
Poignard
Correlation between clinical parameters and development of broadly neutralizing antibody responses.
Public Library of Science
2016
neutralization breadth
IAVI Protocol C program
bnAb responses
vaccine
infection
plasma IgG levels
CD 4 T cell counts
hiv
neutralizing antibody responses
2016-01-28 12:36:25
Figure
https://plos.figshare.com/articles/figure/_Correlation_between_clinical_parameters_and_development_of_broadly_neutralizing_antibody_responses_/1637681
<p>(A) Bivariate and multivariable GLM correlation analyses between the listed variables, and the best neutralization score for the M48+ subset of Protocol C participants. Number of participants in each subgroup (N) is indicated. Estimated coefficients (EstCoef), p-values, q-values, odd ratios (ExpEst) upper (U95) and lower (L95) values of the 95% confidence interval are indicated. P-values are color coded as follows: 0.01< p-value < 0.05, in green; 0.001< p-value < 0.01, in yellow; 2E-16 < p-value <0.001, in red. Q-values below 0.1 are indicated in bold. (B) Kaplan Meier curves recording the time for Protocol C neutralizers (best neutralization score ≥ 0.5, N = 157) within the indicated subgroups to reach a neutralization score ≥ 0.5. Log-Rank test p-values are indicated. DC: Discordant couple, OHS: Other Heterosexual transmission, HSM: Women to Men Heterosexual transmission, HSW: Men to Women Heterosexual transmission, MSM: Men who have Sex with Men.</p>