10.1371/journal.ppat.1005369.g002 Elise Landais Elise Landais Xiayu Huang Xiayu Huang Colin Havenar-Daughton Colin Havenar-Daughton Ben Murrell Ben Murrell Matt A. Price Matt A. Price Lalinda Wickramasinghe Lalinda Wickramasinghe Alejandra Ramos Alejandra Ramos Charoan B. Bian Charoan B. Bian Melissa Simek Melissa Simek Susan Allen Susan Allen Etienne Karita Etienne Karita William Kilembe William Kilembe Shabir Lakhi Shabir Lakhi Mubiana Inambao Mubiana Inambao Anatoli Kamali Anatoli Kamali Eduard J. Sanders Eduard J. Sanders Omu Anzala Omu Anzala Vinodh Edward Vinodh Edward Linda-Gail Bekker Linda-Gail Bekker Jianming Tang Jianming Tang Jill Gilmour Jill Gilmour Sergei L. Kosakovsky-Pond Sergei L. Kosakovsky-Pond Pham Phung Pham Phung Terri Wrin Terri Wrin Shane Crotty Shane Crotty Adam Godzik Adam Godzik Pascal Poignard Pascal Poignard Correlation between clinical parameters and development of broadly neutralizing antibody responses. Public Library of Science 2016 neutralization breadth IAVI Protocol C program bnAb responses vaccine infection plasma IgG levels CD 4 T cell counts hiv neutralizing antibody responses 2016-01-28 12:36:25 Figure https://plos.figshare.com/articles/figure/_Correlation_between_clinical_parameters_and_development_of_broadly_neutralizing_antibody_responses_/1637681 <p>(A) Bivariate and multivariable GLM correlation analyses between the listed variables, and the best neutralization score for the M48+ subset of Protocol C participants. Number of participants in each subgroup (N) is indicated. Estimated coefficients (EstCoef), p-values, q-values, odd ratios (ExpEst) upper (U95) and lower (L95) values of the 95% confidence interval are indicated. P-values are color coded as follows: 0.01< p-value < 0.05, in green; 0.001< p-value < 0.01, in yellow; 2E-16 < p-value <0.001, in red. Q-values below 0.1 are indicated in bold. (B) Kaplan Meier curves recording the time for Protocol C neutralizers (best neutralization score ≥ 0.5, N = 157) within the indicated subgroups to reach a neutralization score ≥ 0.5. Log-Rank test p-values are indicated. DC: Discordant couple, OHS: Other Heterosexual transmission, HSM: Women to Men Heterosexual transmission, HSW: Men to Women Heterosexual transmission, MSM: Men who have Sex with Men.</p>