TY - DATA T1 - A model of the interaction of DR5026 with a bacterial membrane. PY - 2016/01/05 AU - Natalya Panova AU - Eva Zborníková AU - Ondřej Šimák AU - Radek Pohl AU - Milan Kolar AU - Katerina Bogdanova AU - Renata Vecerova AU - Gabriela Seydlová AU - Radovan Fiser AU - Romana Hadravová AU - Hana Šanderová AU - Dragana Vítovská AU - Michaela Šiková AU - Tomáš Látal AU - Petra Lovecká AU - Ivan Barvík AU - Libor Krásný AU - Dominik Rejman UR - https://plos.figshare.com/articles/figure/_A_model_of_the_interaction_of_DR5026_with_a_bacterial_membrane_/1630221 DO - 10.1371/journal.pone.0145918.g009 L4 - https://ndownloader.figshare.com/files/2616744 KW - strain KW - transepithelial transport KW - Bactericidal Lipophosphonoxins KW - cell disintegration KW - Ames test KW - bactericidal concentrations LPPOs KW - compound KW - plasmatic membrane KW - acidic environment N2 - The final state of MD simulation after 55 ns shows DR5026 molecules penetrated into the phospholipid bilayer. The nitrogen atoms from the iminosugar modules of DR5026 are highlighted as blue spheres. Phosphorus atoms of the phospholipid bilayer (PB) are depicted as yellow/red spheres. For clarity, almost all atoms of the PB are hidden. ER -