Expression level of selected miRNA and selection scheme of miR-1290 target genes.
Joanna Janiszewska
Marcin Szaumkessel
Magdalena Kostrzewska-Poczekaj
Kinga Bednarek
Julia Paczkowska
Joanna Jackowska
Reidar Grenman
Krzysztof Szyfter
Malgorzata Wierzbicka
Maciej Giefing
Malgorzata Jarmuz-Szymczak
10.1371/journal.pone.0144924.g001
https://plos.figshare.com/articles/figure/_Expression_level_of_selected_miRNA_and_selection_scheme_of_miR_1290_target_genes_/1629172
<p>A) Overexpression of miR-1290 and miR-1246 in primary LSCC cases (LNA real-time qPCR). B) Schematic presentation of the selection process of miR-1290 candidate genes. C) Expression level of <i>MAF</i>, <i>ITPR2</i> and <i>RGS5</i> in LSCC cell lines and no tumor controls (Affymetrix U133 plus 2.0) based on [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0144924#pone.0144924.ref020" target="_blank">20</a>]. * fold change in LSCC cell lines compared to no tumor controls. D) Expression level of <i>MAF</i> and <i>ITPR2</i> in 22 primary tumor samples compared to 5 no tumor controls.</p>
2016-01-05 14:52:54
miRNA expression
cell carcinoma
ITPR 2
tumor controls.ResultsWithin
Laryngeal Carcinoma BackgroundLaryngeal
bioinformatical approach
9 downregulated miRNA genes
tumor suppressor genes
neck cancers
LSCC pathogenesis
target genes
LSCC cell lines
33 upregulated
target genes MAF