RMSF of the A-loop region and IC<sub>50</sub> values of imatinib for the studied tyrosine kinases and the designed triple mutants of Src.
Silvia Lovera
Maria Morando
Encarna Pucheta-Martinez
Jorge L. Martinez-Torrecuadrada
Giorgio Saladino
Francesco L. Gervasio
10.1371/journal.pcbi.1004578.t001
https://plos.figshare.com/articles/dataset/_RMSF_of_the_A_loop_region_and_IC_50_values_of_imatinib_for_the_studied_tyrosine_kinases_and_the_designed_triple_mutants_of_Src_/1612626
<p>RMSF of the A-loop region and IC<sub>50</sub> values of imatinib for the studied tyrosine kinases and the designed triple mutants of Src.</p>
2015-11-25 03:24:58
binding kinetics
mutation
imatinib resistance
Kinase Conformational Dynamics
T 315I gatekeeper
Drug Resistance
cancer patients
tyrosine kinases
ABL kinase domain
dynamics simulations
Myeloid leukemia
microcalorimetry experiments
DFG motif
energy calculations
binding mechanism
energy landscape