Immunohistochemical labeling for thrombospondin 1.
Harry A. Quigley
Ian F. Pitha
Derek S. Welsbie
Cathy Nguyen
Matthew R. Steinhart
Thao D. Nguyen
Mary Ellen Pease
Ericka N. Oglesby
Cynthia A. Berlinicke
Katherine L. Mitchell
Jessica Kim
Joan J. Jefferys
Elizabeth C. Kimball
10.1371/journal.pone.0141137.g008
https://plos.figshare.com/articles/figure/_Immunohistochemical_labeling_for_thrombospondin_1_/1586593
<p>Immunostaining for thrombospondin-1 shows mild scleral label (arrowheads) in water-treated fellow eye (A) and dramatically increased label in both sclera and retina of water-glaucoma eye (B). Thrombospondin 1 label was less in sclera and retina of both the losartan fellow eye (C) and losartan-glaucoma eye than the corresponding water controls (D, scale bar = 50μm; DAPI counterstain).</p>
2015-10-27 03:50:48
IOP.ConclusionsThe neuroprotective effect
tail cuff device
transcription polymerase chain reaction
RGC loss
angiotensin receptors
3 day IOP elevations
control glaucoma eyes
scleral thickness
regression model p
enalapril
blood pressure
Experimental Glaucoma PurposeTo
Alters Scleral Remodeling
CD 1 mice
Losartan Treatment Protects Retinal Ganglion Cells
losartan treatment decreases
Axonal transport blockade