10.1371/journal.pone.0139850.g005
Kyle P. Glover
Kyle P.
Glover
Zhongqiang Chen
Zhongqiang
Chen
Lauren K. Markell
Lauren
K. Markell
Xing Han
Xing
Han
Pathway enrichment of TPA+UVC gene signature.
Public Library of Science
2015
TK 6 cells
ROPA
tpa
Human lymphoblastoid TK 6 cells
uvc
pcr
protein kinase C
17 gene signature
ap
gene expression patterns
Synergistic Gene Expression Signature Observed
dna
stress response pathways
novel gene signature
tumor microenvironment
qpcr
gene expression signatures
2015-10-02 03:26:28
Figure
https://plos.figshare.com/articles/figure/_Pathway_enrichment_of_TPA_UVC_gene_signature_/1562982
<p>Enrichment of signaling and inflammatory pathways connected by at least one gene in the TPA+UVC gene signature is represented (ConsensusPathDB). The node size is based on number of genes represented in each pathway gene set. The color is determined by statistical enrichment value (darker red = lower p value). The edge thickness represents the total number of genes shared between each pathway with the edge color representing the number of genes in the gene signature shared between each pathway (darker red = more genes). The most significantly enriched pathways were TNFα, TGFβ, IFNγ, p53 and AP-1.</p>