TY - DATA T1 - Nerve fibers in cross sections of the distal colon. PY - 2015/09/23 AU - Ainsley M. Robinson AU - Sarah Miller AU - Natalie Payne AU - Richard Boyd AU - Samy Sakkal AU - Kulmira Nurgali UR - https://plos.figshare.com/articles/figure/_Nerve_fibers_in_cross_sections_of_the_distal_colon_/1554105 DO - 10.1371/journal.pone.0139023.g007 L4 - https://ndownloader.figshare.com/files/2285816 KW - myenteric KW - multipotent differentiation capacity KW - tnbs KW - therapy KW - CM treatments KW - colitis.MethodsAt 3 hours KW - antibody array kit KW - neuroprotective effects KW - body weight loss KW - msc KW - 24 hours post treatment KW - neuroprotective factors N2 - Orderly distribution of fibers labelled by neuron specific anti-β-tubulin (III) antibody was observed in colon sections from sham-treated guinea-pigs at all time points (A-AII). Disorganized, fragmented, and irregularly dispersed fibers were evident within the mucosa of sections from TNBS-only (B-BII) and UCM-treated (E-EII) animals at all time points. Damage to nerve fibers was present in sections from MSC and CM-treated animals at 6 hours (C-D), however re-growth of nerve fibers was observed at 24 (CI-DI) and 72 hours (CII-DII). n = 4/group/time point. Scale bars = 50μm. ER -