Post-TX changes in NF180-labeled neurons.
Guixin Zhang
Li-qing Jin
Jianli Hu
William Rodemer
Michael E. Selzer
10.1371/journal.pone.0137670.g004
https://plos.figshare.com/articles/figure/_Post_TX_changes_in_NF180_labeled_neurons_/1541921
<p>In animals 11–12 cm long, the majority of identified RNs express NF180. The intensity of NF staining and the shapes of neurons did not change dramatically compared to control brain during the first 2 weeks post-TX (<b>A-C</b>). Arrowhead in B points to a Mth axon stump, showing extreme retraction after injury. By 5 weeks post-TX, perikaryal swelling and dendritic shortening and hypertrophy, were seen primarily in bad-regenerating neurons (<b>D-E)</b>. This lasted at least 17 weeks. At 6 months post-TX (<b>F</b>), most of the identified neurons that had shown dramatic swelling previously were no longer seen.</p>
2015-09-14 03:34:21
NF 180 expression
antisense morpholino oligonucleotides
rn
Lamprey Reticulospinal Neurons
Inhibit Axon Regeneration
mo
regeneration
NF expression
axon retraction
tx