%0 Figure %A Jin, Xuewen %A Liu, Yuling %A Liu, Jingjing %A Lu, Weiliang %A Liang, Ziwei %A Zhang, Dan %A Liu, Gang %A Zhu, Hongxia %A Xu, Ningzhi %A Liang, Shufang %D 2015 %T IQGAP1 regulates cell proliferation and migration ability. %U https://plos.figshare.com/articles/figure/_IQGAP1_regulates_cell_proliferation_and_migration_ability_/1506178 %R 10.1371/journal.pone.0133770.g004 %2 https://ndownloader.figshare.com/files/2206040 %K Cell proliferation %K catenin %K IQGAP 1 %K multifunctional scaffold protein %K IQGAP 1 cooperation %K cell metastasis ability %K HCC cell lines %K migration ability %K expression %K rna %X

Overexpression of IQGAP1 in HepG2 cells enhanced cell proliferation (A) and cell migration (C, D). Knockdown of IQGAP1 decreased cell growth (B) and migration (E, F). Control: HepG2 cells transfected with empty pCMV6 plasmids; flag-IQ:HepG2 cells transfected with pFlag-IQGAP1 plasmids. siNC: HepG2 cells transfected with control siRNA; si-IQ: HepG2 cells transfected with IQGAP1 siRNA. Scale bar represents 100 μm (original magnification×200).

%I PLOS ONE