10.6084/m9.figshare.1484674.v1
Mariangela Marrelli
Mariangela
Marrelli
Filomena Conforti
Filomena
Conforti
Francesco Menichini
Francesco
Menichini
Carmen Formisano
Carmen
Formisano
Daniela Rigano
Daniela
Rigano
Nelly Apostolides Arnold
Nelly
Apostolides Arnold
Felice Senatore
Felice
Senatore
Composition, antibacterial, antioxidant and antiproliferative activities of essential oils from three <i>Origanum</i> species growing wild in Lebanon and Greece
Taylor & Francis Group
2015
cancer cell lines
Origanum
antioxidant activity
mic
dpph
frap
dictamnu
2015-07-14 00:00:00
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/Composition_antibacterial_antioxidant_and_antiproliferative_activities_of_essential_oils_from_three_i_Origanum_i_species_growing_wild_in_Lebanon_and_Greece/1484674
<div><p>The essential oils from <i>Origanum dictamnus</i>, <i>Origanum libanoticum</i> and <i>Origanum microphyllum</i> were analysed by GC-MS, finding carvacrol, p-cymene, linalool, γ-terpinene and terpinen-4-ol as major components. The antioxidant activity by the DPPH and FRAP tests and the antiproliferative activity against two human cancer cell lines, LoVo and HepG2, were investigated, showing that the essential oil of <i>O. dictamnus</i> was statistically the most inhibitory on both the cell lines, while all the oils exerted a weak antioxidant activity. Furthermore, the samples were tested against 10 Gram-negative and Gram-positive bacteria; all the oils were active on Gram-positive bacteria but <i>O. dictamnus</i> essential oil was the most effective (MIC = 25–50 μg/mL), showing also a good activity against the Gram-negative <i>Escherichia coli</i> (MIC = 50 μg/mL). Data suggest that these essential oils and particularly <i>O. dictamnus</i> oil could be used as valuable new flavours with functional properties for food or nutraceutical products.</p></div>