%0 Journal Article %A Hegazy, Mohamed-Elamir F. %A M. Gamal-Eldeen, Amira %A Mohamed, Tarik A. %A A. Alhammady, Montaser %A A. Hassanien, Abuzeid %A A. Shreadah, Mohamed %A I. Abdelgawad, Ibrahim %A M. Elkady, Eman %A W. Paré, Paul %D 2015 %T New cytotoxic constituents from the Red Sea soft coral Nephthea sp. %U https://tandf.figshare.com/articles/journal_contribution/New_cytotoxic_constituents_from_the_Red_Sea_soft_coral_i_Nephthea_i_sp_/1480647 %R 10.6084/m9.figshare.1480647 %2 https://ndownloader.figshare.com/files/2172428 %K Nephthea sp. %K terpenes %K cytotoxicity %K breast cancer cell line MCF-7 %X

Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (29). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.

%I Taylor & Francis