%0 Figure %A Chen, Jianquan %A Long, Fanxin %D 2015 %T Osx-cre; Raptorf/fmice exhibited reduced trabecular bone mass. %U https://plos.figshare.com/articles/figure/_Osx_cre_Raptor_f_f_mice_exhibited_reduced_trabecular_bone_mass_/1455358 %R 10.1371/journal.pone.0130627.g005 %2 https://ndownloader.figshare.com/files/2127405 %K osteogenic culture condition %K raptor %K mTORC 1 Signaling Promotes Osteoblast Differentiation %K osteoblast differentiation %K mTORC 1 %X

(A-B) Representative X-ray images of hind limbs of 6 week-old Osx-Cre (Ctrl) (A) or Osx-Cre; Raptorf/f(RapCKO) mice. (B). (C-D) μCT three-dimensional reconstruction of metaphyseal trabecular bone of the tibia from 6 week-old Osx-Cre (Ctrl) (C) or Osx-Cre; Raptorf/f (RapCKO) littermate mice(D). (E-H) μCT quantification of proximal metaphyseal trabecular bone parameters. BV: bone volume; TV: total volume; Tb. N*: trabecular number; Tb. Th*: trabecular thickness; Tb. Sp*: trabecular spacing. Quantification was performed on 100 of 16 μm slices immediately below the growth plate. Ctrl: n = 5; RapCKO: n = 4; *:P<0.05.

%I PLOS ONE