10.1371/journal.pone.0128997.g002 Chris Martini Chris Martini Monique van Velzen Monique van Velzen Asbjørn Drewes Asbjørn Drewes Leon Aarts Leon Aarts Albert Dahan Albert Dahan Marieke Niesters Marieke Niesters Consort flow diagram. Public Library of Science 2015 dorsal horn neurons drug intake peak pain ratings occasions CPM responses randomized controlled trial Healthy Volunteers BackgroundModulatory Conditioned pain modulation placebo influence pain perception ci tapentadol ntr conditioning stimulus min noradrenaline reuptake inhibitor morphine 2015-06-15 02:50:57 Figure https://plos.figshare.com/articles/figure/_Consort_flow_diagram_/1449434 <p>The test stimulus temperatures (heat pain) as determined prior to treatment averaged to 47 ± 0.5°C, 46.6 ± 0.5°C and 46.9 ± 0.5°C on placebo, morphine and tapentadol experimental sessions (one-way anova: NS). The target conditioning stimulus temperatures were 7.9 ± 0.5°C, 8.1 ± 0.6°C and 8.3 ± 0.6°C on placebo, morphine and tapentadol experimental sessions (one-way anova: NS).</p>