%0 Generic %A J. Pena, Michelle %A Heinzel, Andreas %A Heinze, Georg %A Alkhalaf, Alaa %A J. L. Bakker, Stephan %A Q. Nguyen, Tri %A Goldschmeding, Roel %A J. G. Bilo, Henk %A Perco, Paul %A Mayer, Bernd %A de Zeeuw, Dick %A J. Lambers Heerspink, Hiddo %D 2015 %T Concentrations of biomarkers* and univariate and multivariable associations of single biomarkers with eGFR decline. %U https://plos.figshare.com/articles/dataset/_Concentrations_of_biomarkers_and_univariate_and_multivariable_associations_of_single_biomarkers_with_eGFR_decline_/1415619 %R 10.1371/journal.pone.0120995.t001 %2 https://ndownloader.figshare.com/files/2068813 %K ccl %K Renal Function Decline %K eGFR decline %K novel panel %K lasso %K prediction %K outpatient diabetes center %K data integration approach %K YKL %K type 2 diabetes %K disease pathways %K Type 2 Diabetes ObjectiveWe %K ml %K biomarker %K ctgf %K R 2 increase %K Different Disease Pathways %K risk markers %X

*Concentrations of nephrin (NPHS1), neuropilin-1 (NRP1), interleukin-1 alpha (IL1A), interleukin-1 beta (IL1B), and epidermal growth factor (EGF) were missing in 10% of observations or undetectable in >25% of observations, and these biomarkers were therefore not used in analysis.

Adjusted for established risk markers: baseline UACR, current vs. never smoker, sex, systolic blood pressure, use of oral diabetic medication, diastolic blood pressure, and baseline eGFR.

Concentrations of biomarkers* and univariate and multivariable associations of single biomarkers with eGFR decline.

%I PLOS ONE