10.6084/m9.figshare.1412829.v1
Laura P. James
Laura P.
James
Ke Yan
Ke
Yan
Lisa Pence
Lisa
Pence
Pippa M. Simpson
Pippa
M. Simpson
Sudeepa Bhattacharyya
Sudeepa
Bhattacharyya
Pritmohinder Gill
Pritmohinder
Gill
Lynda Letzig
Lynda
Letzig
Gregory L. Kearns
Gregory
L. Kearns
Richard D. Beger
Richard
D. Beger
Comparison of bile acids and acetaminophen protein adducts in children and adolescents with acetaminophen toxicity
figshare
2015
bile acids
Biomarkers
2015-06-03 14:39:13
Dataset
https://figshare.com/articles/dataset/Comparison_of_bile_acids_and_acetaminophen_protein_adducts_in_children_and_adolescents_with_acetaminophen_toxicity/1412829
<p>The relationship of individual bile acids to indicators of oxidative drug metabolism (acetaminophen protein adducts) and liver injury was examined in children with acetaminophen overdose, children with low dose exposure to acetaminophen, and children with no recent exposure to acetaminophen. Targeted metabolomic analysis was used to quantify nine bile acids in the serum samples of children and adolescents among the three groups. Bile acids were compared to serum levels of acetaminophen protein adducts and alanine aminotransferase.</p>