Multicomponent Domino Process for the Synthesis of Some Novel Benzo[<i>a</i>]chromenophenazine Fused Ring Systems Using H<sub>2</sub>SO<sub>4</sub>, Phosphotungstic Acid, and [NMP]H<sub>2</sub>PO<sub>4</sub> M. Rajeswari Garima Khanna Ankita Chaudhary Jitender M. Khurana 10.6084/m9.figshare.1378785.v2 https://tandf.figshare.com/articles/journal_contribution/Multicomponent_Domino_Process_for_the_Synthesis_of_Some_Novel_Benzo_i_a_i_chromenophenazine_Fused_Ring_Systems_Using_H_sub_2_sub_SO_sub_4_sub_Phosphotungstic_Acid_and_NMP_H_sub_2_sub_PO_sub_4_sub_/1378785 <div><p></p><p>Efficient, mild, and quantitative procedures for the synthesis of functionalized benzo[<i>c</i>]chromeno[2,3-<i>a</i>]phenazine derivatives by one-pot, four-component condensation of 2-hydroxynaphthalene-1,4-dione, 1,2-phenylenediamines, aromatic aldehydes, and cyclic 1,3-dicarbonyl compounds have been developed using catalytic amounts of H<sub>2</sub>SO<sub>4</sub> and phosphotungstic acid in EtOH/H<sub>2</sub>O (1:1) under reflux and also with [NMP]H<sub>2</sub>PO<sub>4</sub>, which acts as catalyst and medium at 80 °C. The reaction avoids tedious workup procedure due to the direct precipitation of products from the reaction medium. The present finding provides promising synthetic strategies for the synthesis of libraries with functional group diversity<i>.</i></p></div> 2015-05-05 18:53:32 phenylenediamine fused Multicomponent Domino Process functionalized efficient compound H 2SO group diversity benzo dicarbonyl H 2SO Phosphotungstic strategy hydroxynaphthalene aldehyde synthesis etoh condensation catalyst derivative workup procedure nmp cyclic reflux reaction medium Synthesi phosphotungstic acid