10.6084/m9.figshare.1310476.v2 Zhuya Yang Zhuya Yang Xiaoxia Ma Xiaoxia Ma Wenhong Tan Wenhong Tan Libin Zhou Libin Zhou Xinying Zhuang Xinying Zhuang Shude Yang Shude Yang Zigang Qian Zigang Qian Zhihong Zhou Zhihong Zhou Two new chalcones from <i>Shuteria sinensis</i> Taylor & Francis Group 2015 spectroscopic analysis methods Shuteria sinensis compound 2 D NMR chalcone Glucose metabolism activity 2015-10-08 11:39:16 Journal contribution https://tandf.figshare.com/articles/journal_contribution/Two_new_chalcones_from_i_Shuteria_sinensis_i_/1310476 <div><p>Two new chalcones, 2′,3,4,4′-tetrahydroxy-2-prenylchalcone (<b>1</b>) and 3-methoxy-2′,4,4′-trihydroxy-2-prenylchalcone (<b>2</b>), together with two known compounds, munsericin (<b>3</b>) and 3,4-dihydroxylonchocarpin (<b>4</b>), were isolated from the ethanol extract of the whole plant of <i>Shuteria sinensis</i>. Their structures were identified by spectroscopic analysis methods, such as 1D and 2D NMR, along with HR-MS data. Glucose metabolism activity of four compounds was tested, compounds <b>3</b> and <b>4</b> showed effect on the glucose consumption of insulin-resistant HepG2 cells.</p></div>