%0 Journal Article %A Xu, Jin-Ke %A Lu, Xiang-Hong %A Zhu, Wei %A Yang, Bing-Xian %A Zhang, Lin %A Tian, Jing-Kui %D 2015 %T Two new eudesmane-type glucopyranosides from the fruits of Daucus carota L. %U https://tandf.figshare.com/articles/journal_contribution/Two_new_eudesmane_type_glucopyranosides_from_the_fruits_of_i_Daucus_carota_i_L_/1310473 %R 10.6084/m9.figshare.1310473.v3 %2 https://ndownloader.figshare.com/files/1908281 %K decahydro %K Daucus carota L %K 23.22 %K basis %K glucopyranoside %K compound %K IC 50 values %K chemical evidence %K spectroscopic %K antitumour activity %K eca %K daucucarotol %X

Two new eudesmane-type glucopyranosides have been isolated from the fruits of Daucus carota L. On the basis of their spectroscopic and chemical evidence, the new compounds were elucidated as daucucarotol-10-O-β-d-glucopyranoside (1) and decahydro-7-[(2-O-β-d-glucopyranosyl)-isopropyl]-1β,4aα-dimethyl-(1α,4α,8aβ)-naphthalenetriol (2). Compounds 1 and 2 showed moderate antitumour activity against human ECA-109 and gave IC50 values of 23.22 and 26.76 μM, respectively.

%I Taylor & Francis