TY - DATA T1 - Synthesis of a ditopic homooxacalix[3]arene for fluorescence enhanced detection of heavy and transition metal ions PY - 2015/05/11 AU - Yanan Wu AU - Xin-Long Ni AU - Lan Mou AU - Cheng-Cheng Jin AU - Carl Redshaw AU - Takehiko Yamato UR - https://tandf.figshare.com/articles/journal_contribution/Synthesis_of_a_ditopic_homooxacalix_3_arene_for_fluorescence_enhanced_detection_of_heavy_and_transition_metal_ions/1304856 DO - 10.6084/m9.figshare.1304856.v2 L4 - https://ndownloader.figshare.com/files/1888301 KW - metal cation KW - HTM ions KW - atom effect KW - transition metal KW - spacer KW - ditopic scaffold KW - 1 H NMR titration experiments KW - fluorophore KW - triazole ligands KW - pyrene moiety KW - fluorescence spectra changes KW - monomer emission KW - ionophore KW - transition metal ions KW - emission intensity KW - excimer quenching KW - chemosensor L KW - ions ratiometrically KW - pyrene units move N2 - A pyrene-appended ratiometric fluorescent chemosensor L based on a synthetic approach of insulating the fluorophore from the ionophore by a specific molecular spacer has been synthesised and characterised. The fluorescence spectra changes of L suggested that the chemosensor can detect heavy and transition metal (HTM) ions ratiometrically and with variable sensitivity according to the substituents present. 1H NMR titration experiments indicated that the three triazole ligands prefer binding with Hg2+, Pb2+ and Zn2+, resulting in a conformational change that produces monomer emission of the pyrene accompanied by the excimer quenching. However, the addition of Fe3+, which may be accommodated by the cavity of L, makes the pyrene units move closer to each other, and a discernible increase in the emission intensity of the static excimer is observed. Therefore, it is believed that the ditopic scaffold of the calix[3]arene as a specific molecular spacer here plays an important role in the blocking of the heavy atom effect of HTM ions by insulating the fluorophore from the ionophore given the long distance between the metal cation and the pyrene moiety. ER -