The presence of Müller glia, astrocytes, and endothelial cells of blood vessels in the retina containing photoreceptor-like (PR-L) cells in the subretinal space.
Run-Tao Yan
Li He
Wenjie Zhan
Shu-Zhen Wang
10.1371/journal.pone.0116171.g003
https://plos.figshare.com/articles/figure/_The_presence_of_M_252_ller_glia_astrocytes_and_endothelial_cells_of_blood_vessels_in_the_retina_containing_photoreceptor_like_PR_L_cells_in_the_subretinal_space_/1298489
<p>A–D: Bright-field view (A), DAPI staining of the nuclei (B), and double-immunostaining for Müller proteins GS (C) and CRALBP (D) of a cross-section of the eye from a 2.5-month-old P<sub>RPE65</sub>-ngn3 mouse. E–H: Bright-field view (E), DAPI staining of the nuclei (F), and double-immunostaining for astrocyte protein GFAP (G) and endothelia cells (Endoth) with A10-33/1 (H) of a cross-section of the eye from a 5-month-old P<sub>RPE65</sub>-ngn3 mouse. Scale bar, 50 μm, applies to all panels.</p>
2015-01-30 03:09:41
bipolar cells
ectopic
PAX 6
RPE 65.
nerve head
transcriptional factor
RPE proteins
suppositive strategy
ganglion cells
ciliary body
OTX 2
subretinal space
photoreceptor proteins Crx
Brn 3a
proneural gene neurogenin 1
neurogenin Degeneration
transgenic mice
dna
Transgenic expression
amacrine cells
pigment epithelium
neuron
tissue
RPE 65 promoter
neurogenin 3
regenerative capability
AP 2α
proneural activities