TY - DATA T1 - Sequence divergence and prediction of B-cell linear epitopes and intrinsically unstructured/disordered regions in L. braziliensis Cathepsin L-like and its orthologs. PY - 2015/01/08 AU - Daniel Menezes-Souza AU - Tiago Antônio de Oliveira Mendes AU - Matheus de Souza Gomes AU - Daniella Castanheira Bartholomeu AU - Ricardo Toshio Fujiwara UR - https://plos.figshare.com/articles/figure/_Sequence_divergence_and_prediction_of_B_cell_linear_epitopes_and_intrinsically_unstructured_disordered_regions_in_L_braziliensis_Cathepsin_L_like_and_its_orthologs_/1286639 DO - 10.1371/journal.pntd.0003426.g001 L4 - https://ndownloader.figshare.com/files/1863383 KW - serodiagnosi KW - Synthetic Peptide Containing KW - cathepsin KW - leishmaniasi KW - disease treatment KW - Leishmania parasites KW - Recombinant proteins KW - peptide KW - Leishmania genes KW - Canine Leishmaniasis KW - host proteins KW - epitope KW - surface antigens N2 - Alignment of L. braziliensis Cathepsin L-like (TritrypDB ID: LbrM.08.0830) and orthologous proteins in L. infantum (TritrypDB ID: LinJ.08.0960), T. cruzi (TritrypDB ID: TcCLB.509429.320), H. sapiens (RefSeq ID: NP_003784.2) and C. familiaris (RefSeq ID: XP_005631485.1). The yellow boxes mark predicted B-cell epitopes, and the gray boxes mark predicted disordered regions. The continuous black underlined amino acid sequences in the LbrM.08.0830 protein represent one potential B-cell epitopes predicted by Bepipred, and the colors highlight amino acids conserved between the T. cruzi, C. familiaris and H. sapiens sequences and L. braziliensis. ER -