10.1371/journal.pgen.1004913.g005 Sebastian Treusch Sebastian Treusch Frank W. Albert Frank W. Albert Joshua S. Bloom Joshua S. Bloom Iulia E. Kotenko Iulia E. Kotenko Leonid Kruglyak Leonid Kruglyak Mating type dependent QTL. Public Library of Science 2015 genetic mapping search space Trait locus strain background mapping results mapping approach phenotypic differences mapk genetic variants cerevisiae Signaling pathways phenotypic consequences phenotypic diversity influence phenotypes QTL fall 2015-01-08 03:29:57 Figure https://plos.figshare.com/articles/figure/_Mating_type_dependent_QTL_/1286618 <p>Comparison of allele frequencies within MATa and MATĪ± populations revealed loci that affect growth in a mating type dependent manner. The QTL on chromosome 8 encompasses <i>GPA1</i>, a negative regulator of the mating pathway that affects fitness in different strain backgrounds <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004913#pgen.1004913-Lang1" target="_blank">[50]</a>. Chromosome 3 was omitted as it contains the mating type locus itself (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004913#pgen.1004913.s012" target="_blank">S8 Table</a> for all mating type dependent QTL identified).</p>