10.6084/m9.figshare.1272043.v4
Mansing M. Mane
Mansing
M. Mane
Dattaprasad M. Pore
Dattaprasad
M. Pore
Sulfamic Acid: Efficient, Cost-Effective Catalyst for Facile Synthesis of Deazaoxaflavin at Ambient Temperature
Taylor & Francis Group
2015
Mild reaction conditions
efficient
ecofriendly
barbituric
acid
sulfamic
workup
catalyst
Deazaoxaflavin
synthesis
facile
ambient temperature
separation
scope
deaza
condensation
substrate
yield
ambient
salicylaldehyde
Synthesi
procedure
2015-06-09 19:24:46
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/Sulfamic_Acid_Efficient_Cost_Effective_Catalyst_for_Facile_Synthesis_of_Deazaoxaflavin_at_Ambient_Temperature/1272043
<div><p></p><p>A facile, ecofriendly procedure has been developed for the synthesis of substituted 5-deaza-10-oxaflavins by sulfamic acid–catalyzed two-component condensation of salicylaldehyde and barbituric acid at ambient temperature. Mild reaction conditions, short reaction time, ambient temperature, ecofriendly solvent system, wide substrate scope, simple workup procedure, no need for chromatographic separation, and good yields are auxiliary advantages of the present protocol.</p></div>