10.6084/m9.figshare.1255021.v2
Łukasz J. Binkowski
Łukasz
J. Binkowski
Paweł Rogoziński
Paweł
Rogoziński
Shubhadeep Roychoudhury
Shubhadeep
Roychoudhury
Krzysztof Bruliński
Krzysztof
Bruliński
Marek Kucharzewski
Marek
Kucharzewski
Tomasz Łaciak
Tomasz
Łaciak
Peter Massanyi
Peter
Massanyi
Robert Stawarz
Robert
Stawarz
Accumulation of metals in cancerous and healthy tissues of patients with lung cancer in Southern Poland
Taylor & Francis Group
2014
tissue
aas
concentration
tumor
mg
blood parameters
blood cells numbers
rbc
smoking status
lung cancer
wbc
2014-12-07 01:44:14
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/Accumulation_of_metals_in_cancerous_and_healthy_tissues_of_patients_with_lung_cancer_in_Southern_Poland/1255021
<div><p>The aim of this study was to investigate whether the concentrations of metals differ among patients with and without lung cancer with different smoking status and living in industrialized environments. We also evaluated the relationships between metals and blood parameters including hematocrit level (Hct), hemoglobin concentration (Hb), red (RBC) and white (WBC) blood cells numbers. Concentrations of metals were measured with AAS (copper - Cu, iron - Fe, magnesium - Mg, zinc - Zn) and CV-AAS (mercury - Hg). Neither smoking status nor industrialization could be considered as a significant factor for metals accumulation in blood, lungs and tumor tissues, with the exception of mercury which differed in the aspect of industrialization. According to the type of the disease, Fe, Hg and Mg concentrations differed significantly in lungs. Correlations between metals and blood parameters were observed. Additionally, concentrations of Mg, Cu and Zn were correlated between lungs and tumor tissue of patients with cancer as well as they all were related to each other in lungs, tumor and blood tissues.</p></div>