Further Wnt/β-catenin signaling inhibition sensitizes hypoxic OS cells to doxorubicin. J. Scholten IIDonald TimmerChristine M. D. PeacockJacqueline W. PelleDominic O. WilliamsBart R. SteensmaMatthew 2014 <p>MG-63 OS cells were treated with increasing concentrations of doxorubicin under hypoxic conditions in the presence of the tankyrase inhibitor XAV939, the porcupine inhibitor IWP-2, or DMSO alone. Half maximal inhibitory concentrations (IC<sub>50</sub>) were calculated, and the percent IC<sub>50</sub> relative to DMSO alone was determined. Asterisks indicate statistical significance (*p<0.05).</p>