Cho, Jin-Gyeong Huh, Jeongran Jeong, Rak-Hun Cha, Byeong-Ju Shrestha, Sabina Lee, Dong-Geol Kang, Hee-Cheol Kim, Ji-Young Baek, Nam-In Inhibition effect of phenyl compounds from the <i>Oryza sativa</i> roots on melanin production in murine B16-F10 melanoma cells <div><p>Five phenyl compounds, vanillin (<b>1</b>), methyl <i>trans</i>-ferulate (<b>2</b>), <i>trans</i>-<i>p</i>-coumaric acid methyl ester (<b>3</b>), <i>N</i>-benzoyltryptamine (<b>4</b>), and <i>N</i>-(<i>trans</i>-cinnamoyl)tryptamine (<b>5</b>), were isolated from the roots of <i>Oryza sativa</i> L. and identified on the basis of spectroscopic data. Compounds <b>3</b> and <b>5</b> showed strong inhibition effect on melanin production in murine B16-F10 melanoma cells and tyrosinase activity. Also, the quantitative analysis of the compounds was carried out using LC/MS/MS experiment. Compounds <b>3</b> and <b>5</b> could be used as skin-whitening agents.</p></div> phenyl compounds;lc;melanin production;murine;methyl;Oryza sativa roots;Oryza sativa L;melanoma;Compounds 3 2015-04-28
    https://tandf.figshare.com/articles/journal_contribution/Inhibition_effect_of_phenyl_compounds_from_the_i_Oryza_sativa_i_roots_on_melanin_production_in_murine_B16_F10_melanoma_cells/1198484
10.6084/m9.figshare.1198484.v2