10.1371/journal.pgen.1004572 Andrés Ruiz-Linares Andrés Ruiz-Linares Kaustubh Adhikari Kaustubh Adhikari Victor Acuña-Alonzo Victor Acuña-Alonzo Mirsha Quinto-Sanchez Mirsha Quinto-Sanchez Claudia Jaramillo Claudia Jaramillo William Arias William Arias Macarena Fuentes Macarena Fuentes María Pizarro María Pizarro Paola Everardo Paola Everardo Francisco de Avila Francisco de Avila Jorge Gómez-Valdés Jorge Gómez-Valdés Paola León-Mimila Paola León-Mimila Tábita Hunemeier Tábita Hunemeier Virginia Ramallo Virginia Ramallo Caio C. Silva de Cerqueira Caio C. Silva de Cerqueira Mari-Wyn Burley Mari-Wyn Burley Esra Konca Esra Konca Marcelo Zagonel de Oliveira Marcelo Zagonel de Oliveira Mauricio Roberto Veronez Mauricio Roberto Veronez Marta Rubio-Codina Marta Rubio-Codina Orazio Attanasio Orazio Attanasio Sahra Gibbon Sahra Gibbon Nicolas Ray Nicolas Ray Carla Gallo Carla Gallo Giovanni Poletti Giovanni Poletti Javier Rosique Javier Rosique Lavinia Schuler-Faccini Lavinia Schuler-Faccini Francisco M. Salzano Francisco M. Salzano Maria-Cátira Bortolini Maria-Cátira Bortolini Samuel Canizales-Quinteros Samuel Canizales-Quinteros Francisco Rothhammer Francisco Rothhammer Gabriel Bedoya Gabriel Bedoya David Balding David Balding Rolando Gonzalez-José Rolando Gonzalez-José Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals Public Library of Science 2014 Significant ancestry effects proportion Latin America 2014-09-25 03:58:47 Dataset https://plos.figshare.com/articles/dataset/_Admixture_in_Latin_America_Geographic_Structure_Phenotypic_Diversity_and_Self_Perception_of_Ancestry_Based_on_7_342_Individuals_/1183040 <div><p>The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification. We estimated individual ancestry proportions in a sample of 7,342 subjects ascertained in five countries (Brazil, Chile, Colombia, México and Perú). These individuals were also characterized for a range of physical appearance traits and for self-perception of ancestry. The geographic distribution of admixture proportions in this sample reveals extensive population structure, illustrating the continuing impact of demographic history on the genetic diversity of Latin America. Significant ancestry effects were detected for most phenotypes studied. However, ancestry generally explains only a modest proportion of total phenotypic variation. Genetically estimated and self-perceived ancestry correlate significantly, but certain physical attributes have a strong impact on self-perception and bias self-perception of ancestry relative to genetically estimated ancestry.</p></div>