%0 Journal Article %A Rao Kaki, Venkata %A Rao Akkinepalli, Raghuram %A Kishore Deb, Pran %A Rao Pichika, Mallikarjuna %D 2014 %T Basic Ionic Liquid [bmIm]OH–Mediated Gewald Reaction as Green Protocol for the Synthesis of 2-Aminothiophenes %U https://tandf.figshare.com/articles/journal_contribution/Basic_Ionic_Liquid_bmIm_OH_8211_Mediated_Gewald_Reaction_as_Green_Protocol_for_the_Synthesis_of_2_Aminothiophenes/1181985 %R 10.6084/m9.figshare.1181985.v3 %2 https://ndownloader.figshare.com/files/1690414 %K alkoxy %K Basic %K aminothiophene %K variety %K alkylamino %K Green Protocol %K method %K synthesis %K bmim %K catalyst %K alkyl %K yield %K aryl %K Gewald reaction %K Synthesi %K procedure %X

A simple, efficient, and environmental friendly procedure was developed based on the Gewald reaction for the synthesis of 2-aminothiophenes using a basic ionic liquid [bmIm]OH as both catalyst and solvent. Besides being a green protocol, the method offers advantages of successful synthesis of a variety of alkyl, aryl, alkoxy, and alkylamino-2-aminothiophenes in good yields.

%I Taylor & Francis