10.6084/m9.figshare.11805963.v1
Tural Aksel
Tural
Aksel
Nick Fong
Nick
Fong
Christopher Maffeo
Christopher
Maffeo
Aleksei Aksimentiev
Aleksei
Aksimentiev
Shawn Douglas
Shawn
Douglas
SI2:SSE: Collaborative Research: Integrated Tools for DNA Nanostructure Design and Simulation
figshare
2020
NSF-CSSI-2020-Talk
DNA origami
Biophysics
Simulation and Modelling
Nanotechnology not elsewhere classified
2020-02-05 06:09:35
Presentation
https://figshare.com/articles/presentation/SI2_SSE_Collaborative_Research_Integrated_Tools_for_DNA_Nanostructure_Design_and_Simulation/11805963
While the robustness of the DNA origami method has enabled researchers
to fabricate a large diversity of shapes, many design choices are made
according to <i>ad hoc</i> rules and heuristics derived from limited
empirical data. It would be beneficial to establish a quantitative
physical basis for favoring one strand routing over another for a given
shape. With these goals in mind, we have developed Cadnano Toolkit (<b>CTK</b>) and Molecular Dynamics Simulations of Self-Assembled DNA Nanostructures (<b>MrDNA</b>), a suite of programs to augment several aspects of the DNA origami design process.<br>