Haemolysis and acanthocytosis in <i>ms/−</i> mice.
Małgorzata Lenartowicz
Rafał R. Starzyński
Wojciech Krzeptowski
Paweł Grzmil
Aleksandra Bednarz
Mateusz Ogórek
Olga Pierzchała
Robert Staroń
Anna Gajowiak
Paweł Lipiński
10.1371/journal.pone.0107641.g002
https://plos.figshare.com/articles/figure/_Haemolysis_and_acanthocytosis_in_ms_8722_mice_/1178946
<p>(<b>A</b>) Serum of control (<i>+/−</i>) and mutant (<i>ms/−</i>) males obtained by centrifugation. (<b>B</b>) Peripheral blood smears of <i>ms/−</i> mice showing increased numbers of acanthocytes. High magnification images of a normal and an abnormally-shaped erythrocyte are shown (insets). Six animals from both the control and <i>ms/−</i> male groups were examined and one typical sample of each is shown. Bars correspond to 5 µm. (<b>C</b>) Plasma levels of haptoglobin (Hp) were assessed by western blotting as described in the Experimental section. The blot was reprobed with monoclonal anti-actin antibody as a loading control.</p>
2014-09-23 03:14:47
copper deficiency
mosaic mice show evidence
haem oxygenase 1
ho
Iron Metabolism
Reactive oxygen species
Menke
cell membrane abnormalities
antioxidant enzyme scavenges
ATP 7A copper transporter
sod
Systemic Iron Metabolism
superoxide dismutase 1