10.6084/m9.figshare.1172164.v2 Chitturi Bhujanga Rao Chitturi Bhujanga Rao Dokuburra Chanti Babu Dokuburra Chanti Babu Tatipamula Vinay Bharadwaj Tatipamula Vinay Bharadwaj Dudem Srikanth Dudem Srikanth Kalivendi Shasi Vardhan Kalivendi Shasi Vardhan Tuniki Venugopal Raju Tuniki Venugopal Raju Richard A. Bunce Richard A. Bunce Yenamandra Venkateswarlu Yenamandra Venkateswarlu Isolation, structural assignment and synthesis of (<i>S</i><i>E</i>)-2-methyloctyl 3-(4-methoxyphenyl) propenoate from the marine soft coral <i>Sarcophyton ehrenbergi</i> Taylor & Francis Group 2014 du synthesis marine Sarcophyton ehrenbergi mcf se 2014-10-30 11:54:39 Journal contribution https://tandf.figshare.com/articles/journal_contribution/Isolation_structural_assignment_and_synthesis_of_i_S_i_i_E_i_2_methyloctyl_3_4_methoxyphenyl_propenoate_from_the_marine_soft_coral_i_Sarcophyton_ehrenbergi_i_/1172164 <div><p>A new metabolite <b>1</b> has been isolated from the marine soft coral <i>Sarcophyton ehrenbergi</i> along with two known diterpenoids <b>2</b> and <b>3</b> and cholesterol <b>4</b>. The structure of <b>1</b> was determined by means of detailed spectroscopic analysis and unambiguously confirmed to have the <i>S</i> configuration by the synthesis of both enantiomers using 4-benzyl-2-oxazolidinone auxiliaries. (<i>S</i>)- and (<i>R</i>)-<b>1</b>, <b>3</b> and some of the synthetic intermediates were evaluated for cytotoxic activity against human lung cancer (A549), prostate cancer (DU145), cervical cancer (HeLa) and breast cancer (MCF-7) cell lines in an <i>in vitro</i> bioassay.</p></div>