Duan, Yankun Chen, Lin Chen, Yongheng Fan, Xue-gong Structure comparison of c-Src and JAK1 structures. <p>(A) c-Src kinase domain (this work) is superimposed with JAK1 kinase domain (pdb: 3EYG) using the Ca atoms of kinase domain as the reference. c-Src is shown yellow, while JAK1 is shown in magenta. (B) Predicted c-Src ligand-binding pocket is shown in grey dots. (C) Predicted JAK1 ligand-binding pocket is shown in grey dots. Ligand-binding pocket is predicted using POCASA<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0106225#pone.0106225-Yu1" target="_blank">[30]</a>.</p> van der Waals contacts;janus kinase inhibitor;Cancer Drug Ruxolitinib;JAK 1;Ruxolitinib binding;JAK 1 structure 2014-09-08
    https://plos.figshare.com/articles/figure/_Structure_comparison_of_c_Src_and_JAK1_structures_/1165096
10.1371/journal.pone.0106225.g005