TY - DATA T1 - Effect of NAC on the metabolic changes induced by osteopontin-c on deadherent cells. PY - 2014/08/26 AU - Zhanquan Shi AU - Bo Wang AU - Tafadzwa Chihanga AU - Michael A. Kennedy AU - Georg F. Weber UR - https://plos.figshare.com/articles/dataset/_Effect_of_NAC_on_the_metabolic_changes_induced_by_osteopontin_c_on_deadherent_cells_/1151992 DO - 10.1371/journal.pone.0105675.t004 L4 - https://ndownloader.figshare.com/files/1650636 KW - cancer cells KW - metastasis gene osteopontin KW - glutamine KW - tricarboxylic acid cycle KW - creatine KW - glycerol phosphate shuttle KW - hexose monophosphate shunt KW - Invasive tumor cells KW - mitochondrial ATP production KW - Energy metabolism KW - pathway N2 - MCF-7 cells transfected with osteopontin-c or vector control were plated in poly-HEMA coated wells. 4 mM N-acetyl L-cysteine was added to one sample of MCF-7 OPNc cells. After 48 hours, the cells were harvested and lysed for analysis of the metabolite levels by NMR. Shown are comparison of MCF-7 OPNc (C) to MCF-7 vector (V), comparison of MCF-7 OPNc + NAC to MCF-7 vector, comparison of MCF-7 OPNc to MCF-7 OPNc + NAC.Effect of NAC on the metabolic changes induced by osteopontin-c on deadherent cells. ER -