The TCF binding sites are required for expression of the Tig and minR reporters in embryonic hemocytes. Chen U. Zhang Timothy A. Blauwkamp Peter E. Burby Ken M. Cadigan 10.1371/journal.pgen.1004509.g012 https://plos.figshare.com/articles/figure/_The_TCF_binding_sites_are_required_for_expression_of_the_Tig_and_minR_reporters_in_embryonic_hemocytes_/1147829 <p>(<b>A–I</b>) Confocal images of stage 15 embryos containing wild-type minR reporter (A–C) and the Hm (D–F) or Wm (G–I) mutants, with immunofluorescence detection of LacZ (green) and MDP-1 (red). Expression of the reporter is greatly reduced when either motif is mutated.</p> 2014-08-21 03:37:13 High Mobility Group repression tcf controls prohemocytic differentiation DNA binding domains protease digestion studies domain binding HMG sites target gene expression Bipartite DNA Recognition Helper sites mechanism Drosophila Hematopoietic System Wnt transcriptional responses