The TCF binding sites are required for expression of the Tig and minR reporters in embryonic hemocytes.
Chen U. Zhang
Timothy A. Blauwkamp
Peter E. Burby
Ken M. Cadigan
10.1371/journal.pgen.1004509.g012
https://plos.figshare.com/articles/figure/_The_TCF_binding_sites_are_required_for_expression_of_the_Tig_and_minR_reporters_in_embryonic_hemocytes_/1147829
<p>(<b>A–I</b>) Confocal images of stage 15 embryos containing wild-type minR reporter (A–C) and the Hm (D–F) or Wm (G–I) mutants, with immunofluorescence detection of LacZ (green) and MDP-1 (red). Expression of the reporter is greatly reduced when either motif is mutated.</p>
2014-08-21 03:37:13
High Mobility Group
repression
tcf
controls prohemocytic differentiation
DNA binding domains
protease digestion studies
domain binding HMG sites
target gene expression
Bipartite DNA Recognition
Helper sites
mechanism
Drosophila Hematopoietic System
Wnt transcriptional responses